Degradation of D-Glutamic Acid in Bacterium

The estimation of D- and L-glutamic acid in proteins.

Brand, E., Harris, M. M. & Biloon, S. (1930). J. biol. Chem. 86, 315. Challenger, F. & Simpson, M. I. (1947). Biochem. J. 41, xl. Challenger, F. & Simpson, M, I. (1948). J. chem. Soc. p. 1591. Crum Brown, A. & Fraser, T. R. (1872). Trans. Roy. Soc. Edinb. 7, 663. Du Vigneaud, V. (1942-3). Harvey Lect. 39. Du Vigneaud, V., Moyer, A. W. & Chandler, J. P. (1948). J. biol. Chem. 174, 477. Dubnoff, ...

Macrophage uptake, intracellular localization, and degradation of poly-gamma-D-glutamic acid, the capsular antigen of Bacillus anthracis.

Bacillus anthracis is surrounded by a capsular polypeptide composed of poly-gamma-D-glutamic acid (PGA). This antiphagocytic capsule is an essential virulence factor and is shed into body fluids during a murine model of pulmonary anthrax. Our previous studies of a murine model for antigen clearance showed that purified PGA accumulates in the liver and spleen, most notably in splenic macrophages...

Determination of Glutamic Acid

Glutamic Acid Dehydrogenase and Glutamic-oxalacetic

As part of a larger project dealing with an in vestigation of amino acid and protein metabolism in leukemia, a study was undertaken to determine those enzymes concerned with amino acid anabo lism and catabolism as they occur in selected tis sues. Several review papers (@,4, 11, 1@)have ade quately summarized our present knowledge of the metabolism of white blood cells (WBC) in leuke mia. Howeve...

Glutamic Acid in Malignant Tumors

The ultimate solution of the problem of cancer will probably involve the recognition of specific chemical differences between the modes of development of normal and of neoplastic cellular tissues. The growth of a tissue comprises the synthesis of protein from the natural amino acids. It has in the past few years become amply clear that all amino acids occurring in proteins have the same “natura...